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2 Molecular mechanisms of GLP-1 Action 2.1 GLP-1 Receptor structure and signalling The GLP-1 receptor (GLP-1R), a G-protein-coupled receptor, activates a complicated signalling cascade upon the interaction of GLP-1 (Fig

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The ominous octet, which includes 8 key pathophysiologic defects found to be present in T2D, is illustrated in Figure 1